Expression of testis-specific genes, TEX101 and ODF4 , in chronic myeloid leukemia and evaluation of TEX101 immunogenicity
نویسندگان
چکیده
منابع مشابه
Expression of Testis Specific Genes TSGA10, TEX101 and ODF3 in Breast Cancer
BACKGROUND Breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. Cancer testis genes are a group of genes expressed solely in testis and in a range of human malignancies. OBJECTIVES In this study we determined the expression of cancer testis genes Tsga10, TEX101 and ...
متن کاملexpression of testis specific genes tsga10, tex101 and odf3 in breast cancer
background breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. cancer testis genes are a group of genes expressed solely in testis and in a range of human malignancies. objectives in this study we determined the expression of cancer testis genes tsga10, tex101 and od...
متن کاملInvestigation of SMAD3 and SMAD4 genes expression in CML patients and K562 cell line and association with chronic myeloid leukemia
Aim and Background: Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder with cytogenetic characterization of the abnormal Philadelphia chromosome. This chromosome results from a reciprocal translocation between chromosomes 9 and 22. This is an important signaling pathway in the process of cancer cell proliferation and apoptosis, as well as the pathogenesis of TGF-β disease, i...
متن کاملInvestigating specific expression of ADAM29, FTHL17, and HORMAD1 cancer/testis genes in glioblastoma tumors
Introduction: Glioblastoma primary brain tumor.Immunotherapy is a promising therapeutic adjuvant in fighting against this cancer. Cancer/testis antigens (CTAs) are a group of tumor-associated antigens that are typically restricted to adult testis, but they are aberrantly expressed in several types of cancers, especially in advanced cancers with stem-like characteristics. These tumor-associate...
متن کاملIdentification and Characterization of TEX101 in Bovine Epididymal Spermatozoa
Several studies exhibit the presence of Ricinus Communis Agglutinin I (RCA) binding glycocalyx in mammalian spermatozoa. However, the molecular characterization of RCA binding glycocalyx in sperm membranes and its mechanism of action are poorly understood. The objective of the study was to identify and to characterize RCA binding glycoprotein of the bovine sperm plasma membranes (PM). Lectin bl...
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ژورنال
عنوان ژورنال: Annals of Saudi Medicine
سال: 2012
ISSN: 0256-4947,0975-4466
DOI: 10.5144/0256-4947.2012.256